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Papers

Most recent

Freiberger T., Svoboda M., Malisova B., Cernochova M., Nemcova E., Burysek L., Nemec P.: P39 New System of Microarray-based Detection of Bacterial Pathogens in Heart Tissue Samples, International Journal of Antimicrobial Agents. 41:S18.

On bioavailability and metabolism

Kusala S., Janku I., Elis J., Svobodova X., Stara D., Kamenska R., Ostrovska V.: Relative bioavaiability and pharmacokinetics of pentoxifylline after administration of Agapurin retard and Trental 400., Res.Pharma, 7,75, 1985

Mahrla Z., Augustiniova J., Sidlikova I., Ostrovska O., Kovacova D., Svobodova X., Baricic P.: Pharmacokinetic and bioavailability of dispensing forms of mexiletine in dogs., Res.Pharma, 12, 47, 1987.

L. Mendoza, M. Hajduch, R. Plausinajtis, V. Platilova, N. Emrite, M. Svoboda: Bioequivalence of two brands of citalopram 40 mg after single oral administration to healthy volunteers. Biomed. Papers, 149(1), 169-172, 2005 - several new potential metabolites identified

L. Mendoza, M. Hajduch, R. Plausinajtis, V. Platilova, N. Emrite, M. Svoboda: Pharmacokinetic and bioequivalence testing of atorvastatin formulations in healthy male voluntieers. Pharmazie 61, 805-806, 2006

On analytical methods

Svoboda M., Vacik J.: Capillary isotachophoresis with UV detection. Some quantitative aspects., J. Chromatogr., 119, 539, 1976. - pioneering work dealing with the effect of finite detection slit width and cylindrical shape of the detection cell

Svobodova X., Svoboda M.: Testmethoden für UV-VIS Spectrophotometer., Jenaer Rundschau, 25(3), 196, 1981.

Svoboda M.: Die relative und indirekte Standardisierung mit der Kapillarelektrophorese., Zbl. Pharm. Pharmakoter., Laboratoriumdiagn.,120, 167, 1981.

Svoboda M., Svobodova X., Vacik J.: Some quantitative aspects of UV detection in capillary isotachophoresis as applied to bioavaiability studies., J. Chromatogr., 273, 228, 1983.

Ostrovska O., Svobodova X., Pechova A.,Svoboda M., Kusala S.: Optimization of fluo-rescence detection for the determination of labetalol in plasma by high performance liquid chromatography., J. Chromatogr. 446, 323, 1988.

Svobodova X., Kovacova D., Ostrovska V., Pechova A., Polackova O., Kusala S., Svoboda M.: Determination of nitroglycerin in human plasma using bonded phase capillary column gas chromatography with electron capture detector., J. Chromatogr. 425(2), 391, 1988 - pioneering work in pg level quantification of nitroglycerin and metabolites

Ostrovska O., Pechova A., Svobodova X.: Determination of etofyllineclofibrate in plasma by reversed phase HPLC., J. Liq. Chromatogr., 12(14), 2793, 1989

Svoboda M., Musil S.: Speciation of polyhydroxycompounds by gas chromatography mass spectrometry with deuterium oxide chemical ionisation., J. Chromatogr., 520, 209, 1990.

On biophysical chemistry

Svobodova X., Karpenko V., Kalous. V.: Alkaline denaturation of orosomucoid studied by the stopped flow and temperature jump method., Coll. Czech. Chem. Commun., 41. 3822, 1976.

Svobodova X., Karpenko V., Kalous. V: On the kinetics of alkaline denaturation of orosomucoid., Coll. Czech. Chem. Commun., 42. 1742, 1977.

Pospisil M., Kovar P., Vacha R., Svoboda M.: Study of Betulin Molecule in Water Environment. Ab initio and Molecular Simulation Calculations. Journal of Molecular Modeling, 2011, J Mol Model [online], 03.May 2011

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